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Primary and radiation induced skull base osteosarcoma: a systematic review of clinical features and treatment outcomes.

Othman Bin AlamerAli S HaiderMaryam HaiderNavraj S SagooFaith C RobertsonEliel N ArreySalah G AounKenny YuAaron A Cohen-GadolTarek Y El Ahmadieh
Published in: Journal of neuro-oncology (2021)
SBO is a malignant disease with poor survival outcomes. Surgical resection is the primary management modality, in conjunction with chemotherapy and radiotherapy. Radiation-induced SBO has a superior survival outcome as compared to its primary counterpart. Complete surgical resection showed a statistically insignificant survival benefit as compared to partial resection.
Keyphrases
  • radiation induced
  • radiation therapy
  • locally advanced
  • early stage
  • squamous cell carcinoma