Explore on the Mechanism of miRNA-146a/TAB1 in the Regulation of Cellular Apoptosis and Inflammation in Ulcerative Colitis Based on NF-κB Pathway.

Xiaoying XiaQian YangXue HanYulin DuShujun GuoMengqing HuaFang FangZhigang MaHua MaHui YuanWenjing TianZebang DingYanan DuanQi HuoYao Li

Published in: Current molecular medicine (2024)

MiR-146a knockdown inhibited cell apoptosis and inflammation via targeting TAB1 and suppressing NF-κB pathway, suggesting that miR-146a may be a new therapeutic target for UC treatment.

Keyphrases

oxidative stress
cell proliferation
signaling pathway
long non coding rna
pi k akt
ulcerative colitis
long noncoding rna
lps induced
cell cycle arrest
nuclear factor
endoplasmic reticulum stress
cell death
cancer therapy
immune response
combination therapy
smoking cessation