Maurice PasternakSaira S MirzaNicholas LuciwHenri J M M MutsaertsJan PetrDavid ThomasDavid CashMartina BocchettaMaria Carmela TartagliaSara B MitchellSandra E BlackMorris FreedmanDavid Tang-WaiEkaterina RogaevaLucy L RussellArabella BouziguesJohn C van SwietenLize C JiskootHarro SeelaarRobert LaforcePietro TiraboschiBarbara BorroniDaniela GalimbertiJames B RoweCaroline GraffElizabeth FingerSandro SorbiAlexandre de MendonçaChris ButlerAlex GerhardRaquel Sanchez-ValleFermin MorenoMatthis SynofzikRik VandenbergheSimon DucharmeJohannes LevinMarkus OttoIsabel SantanaAntonio P StrafellaBradley J MacIntoshJonathan D RohrerMario Masellisnull null
Published in: Alzheimer's & dementia : the journal of the Alzheimer's Association (2024)
Gray matter perfusion declines in at-risk genetic frontotemporal dementia (FTD). Regional perfusion decline differs between at-risk genetic FTD subgroups . Hypoperfusion in the left thalamus is common across all presymptomatic groups. Converters exhibit greater right frontal hypoperfusion than non-converters past their expected conversion date. Cerebral hypoperfusion is a potential early biomarker of genetic FTD.