Accurate pH Sensing using Hyperpolarized 129 Xe NMR Spectroscopy.
Estelle LéonceJean-Pierre DognonDelphine PitratJean-Christophe MulatierThierry BrotinPatrick BerthaultPublished in: Chemistry (Weinheim an der Bergstrasse, Germany) (2018)
In the search for powerful non-invasive methods for pH measurement, NMR usually suffers from biases, especially for heterogeneous samples or tissues. In this Communication, using the signals of hyperpolarized 129 Xe encapsulated in a pair of water-soluble cryptophanes, we show that a differential pH measurement can be achieved, free from most of these biases, by monitoring the difference between their chemical shifts.