Mitochondrial GWAS and association of nuclear - mitochondrial epistasis with BMI in T1DM patients.
Agnieszka H Ludwig-SłomczyńskaMichał T SewerynPrzemysław KapustaEwelina PiteraSamuel K HandelmanUrszula MantajKatarzyna CyganekPaweł GutajŁucja DobruckaEwa Wender-OżegowskaMaciej T MałeckiPawel P WolkowPublished in: BMC medical genomics (2020)
Here, we have shown that variants in the mitochondrial genome as well as additive interactions between mitochondrial and nuclear SNPs influence BMI in T1DM and general cohorts.
Keyphrases
- oxidative stress
- end stage renal disease
- body mass index
- chronic kidney disease
- newly diagnosed
- ejection fraction
- genome wide
- weight gain
- prognostic factors
- gene expression
- patient reported outcomes
- metabolic syndrome
- skeletal muscle
- insulin resistance
- weight loss
- genome wide association study
- genome wide association