Brimonidine displays anti-inflammatory properties in the skin through the modulation of the vascular barrier function.
Béatrice BertinoSandrine Blanchet-RéthoréSéverine Thibaut de MénonvillePhilippe ReynierBruno MéhulAudrey BogouchBastien GamboaAnne Sophie DugaretDidier ZugajLaurent PetitManon RoquetDavid PiwnicaEmmanuel VialValerie BourdèsJohannes J VoegelChristelle NonnePublished in: Experimental dermatology (2019)
Results from in vitro, in vivo and from a clinical study indicate that brimonidine impacts acute inflammation of the skin by interfering with neurogenic activation and/or recruitment of neutrophils.