Associations of polygenic risk scores with risks of stroke and its subtypes in Chinese.
Songchun YangZhijia SunDong SunCanqing YuYu GuoDianjianyi SunYuanjie PangPei PeiLing YangIona Y MillwoodRobin G WaltersYiping ChenHuaidong DuYan LuSushila BurgessDaniel AveryRobert J ClarkeJunshi ChenZhengming ChenLiming LiJun Lvnull nullPublished in: Stroke and vascular neurology (2023)
In this Chinese population, the association strengths of current PRSs with risks of stroke and its subtypes were moderate, suggesting a limited value for improving risk prediction over traditional risk factors in the context of current genome-wide association study under-representing the East Asian population.