High-Yielding Water-Soluble Asymmetric Cyanine Dyes for Labeling Applications.

Natalia WolfLouise KerstingChristoph HerokCornelius MihmJuergen Seibel
Published in: The Journal of organic chemistry (2020)
A simple and efficient microwave-assisted synthesis of asymmetric pentamethine cyanine dyes with various functional groups was developed, which allows high-yielding results. The synthesized dyes are modifiable and suitable for single-molecule imaging in biological and medical sciences by application of click chemistry or classic esterification and amidation.