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Long-term Sudan virus Ebola survivors maintain multiple antiviral defense mechanisms.

Ariel SobarzoYves MoneSteven LangSigal GelkopPolina BrangelAna I KuehneRachel A McKendryJoshua Chang MellAzad AhmedClaytus DavisJohn M DyeJulius Julian LutwamaLeslie LobelFrancisco VeasGarth D Ehrlich
Published in: The Journal of infectious diseases (2023)
Data integration identified significant correlations among humoral and cellular immune responses and pinpointed a specific innate and adaptive gene expression signature associated with long-lasting immunity. This could help identify natural and vaccine correlates of protection against ebolavirus disease.
Keyphrases
  • immune response
  • gene expression
  • dna methylation
  • dendritic cells
  • electronic health record
  • young adults
  • toll like receptor
  • big data
  • data analysis
  • inflammatory response