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Evaluation of the protective properties and genotoxic potential of pyrazolo pyridine derivatives against neutron and gamma radiation using the Ames/ Salmonella test system.

Bünyamin AygünBurak AlaylarKadir TurhanMehmet KaradayıEsra CinanZuhal TurgutTansu SezerVedat SolaTaha Yasin KocAbdulhalik Karabulut
Published in: International journal of radiation biology (2024)
All obtained results indicate that all PPC (pyrazolo[3,4-b] pyridine derivatives) samples do not possess a toxic effect, and they can be utilized as an active substance for the development of a drug or cream with protective properties against both gamma and neutron radiations.
Keyphrases
  • escherichia coli
  • structure activity relationship
  • emergency department
  • listeria monocytogenes
  • radiation induced
  • risk assessment
  • adverse drug