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Leaf extracts from Dendropanax morbifera Léveille mitigate mercury-induced reduction of spatial memory, as well as cell proliferation, and neuroblast differentiation in rat dentate gyrus.

Woosuk KimDae Young YooHyo Young JungJong Whi KimKyu Ri HahnHyun Jung KwonMiyoung YooSanghee LeeSung Min NamYeo Sung YoonDae Won KimIn-Koo Hwang
Published in: BMC complementary and alternative medicine (2019)
These results suggest that DML may be a functional food that improves dimethylmercury-induced memory impairment and ameliorates dimethylmercury-induced reduction in proliferating cells and differentiated neuroblasts, and demonstrates corresponding activation of AChE activity in the dentate gyrus.
Keyphrases
  • high glucose
  • cell proliferation
  • diabetic rats
  • oxidative stress
  • working memory
  • induced apoptosis
  • endothelial cells
  • mouse model
  • cell cycle
  • signaling pathway
  • climate change
  • human health