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Bioprospecting of desert actinobacteria with special emphases on griseoviridin, mitomycin C and a new bacterial metabolite producing Streptomyces sp. PU-KB10-4.

Maira SaleemAshba HassanFeina LiQinpei LuLarissa V PonomarevaSean ParkinChenghang SunJon S ThorsonKhaled A ShaabanImran Sajid
Published in: BMC microbiology (2023)
This is the first report of the bioprospecting and exploration of actinobacteria from Kubuqi desert and the metabolite 4-hydroxycinnamide (3) is first time isolated from a bacterial source. This study demonstrated that actinobacteria from Kubuqi desert are a potential source of novel bioactive natural products. Underexplored harsh environments like the Kubuqi desert may harbor a wider diversity of actinobacteria, particularly Streptomyces, which produce unique metabolites and are an intriguing source to develop medicinally valuable natural products.
Keyphrases
  • ms ms
  • risk assessment
  • human health