Study of Excipients in Delayed Skin Reactions to mRNA Vaccines: Positive Delayed Intradermal Reactions to Polyethylene Glycol Provide New Insights for COVID-19 Arm.
David PesquéRamon Maria PujolOrianna MarcantonioAinhoa Vidal-NavarroJosé María RamadaAlba Arderiu-FormentíAgustí Albalat-TorresConsol SerraGimenez-Arnau Ana MariaPublished in: Vaccines (2022)
Immediate and delayed reactions to IDT are frequently detected in patients with DLLR. The observation of positive delayed intradermal reactions to PEG disclosed only in patients with DLLR reinforces a possible role of PEG in the development of these reactions. Skin testing of other excipients is of little importance in clinical practice.