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TCP post-radioembolization and TCP post-EBRT in HCC are similar and can be predicted using the in vitro radiosensitivity.

Philippe d'AbadieStephan WalrandMichel HesseIvan BorbathRenaud LhommelFrançois Jamar
Published in: EJNMMI research (2022)
Y TOF-PET/CT predicts the metabolic response post-RE in HCC assessed using dual molecular PET tracers and provides a similar TCP curve to that observed in EBRT. In vivo and in vitro HCC radiosensitivities are similar. Both TCPs show that a EUD of 100 Gy is needed to control HCC for the three devices (resin spheres, glass spheres, EBRT). Observed absorbed doses achieving this 100 Gy-EUD ranged from 190 to 1800 Gy!
Keyphrases
  • pet ct
  • positron emission tomography
  • computed tomography
  • mass spectrometry
  • ms ms
  • pet imaging