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Evaluating the efficacy and safety of topical sirolimus 0.2% cream as adjuvant therapy with pulsed dye laser for the treatment of port wine stain: A randomized, double-blind, placebo-controlled trial.

Mahsa FallahiZahra HallajiSoheil TavakolpourSomayeh NiknamAli Salehi FaridAli NiliAmir TeimourpourMaryam DanespazhoohJavad RahmatiShahriar Haddady AbianehHamid Reza Mahmoudi
Published in: Journal of cosmetic dermatology (2020)
Although the improvement was significant subjectively, topical sirolimus 0.2% as an adjuvant to PDL does not appear to improve PWS erythema using calorimetric assessment.
Keyphrases
  • double blind
  • placebo controlled
  • clinical trial
  • study protocol
  • phase iii
  • highly efficient
  • mass spectrometry
  • combination therapy
  • phase ii
  • open label
  • laparoscopic surgery
  • aqueous solution