Gut Dysbiosis Shaped by Cocoa Butter-Based Sucrose-Free HFD Leads to Steatohepatitis, and Insulin Resistance in Mice.
Shihab KochumonR K Brojen SinghSardar SindhuHossein ArefanianTexy JacobFatemah BahmanRasheeba NizamAmal HasanReeby ThomasFatema Al-RashedSteve ShenoudaAjit WilsonShaima AlbeloushiNourah AlmansourGhadeer AlhamarAshraf Al MadhounFawaz AlzaidThangavel Alphonse ThanarajHeikki A KoistinenJaakko TuomilehtoFahd Al-MullaRasheed AhmadPublished in: Nutrients (2024)
These findings suggest that the sucrose-free C-HFD feeding in mice induces gut dysbiosis which associates with liver inflammation, steatosis, glucose intolerance and insulin resistance.