Evaluation of a novel CFTR potentiator in COPD ferrets with acquired CFTR dysfunction.
Niroop KazaVivian Y LinDenise StanfordShah Saddad HussainEmily Falk LibbyHarrison KimMonica BorgonoviKatja ConrathVenkateshwar MutyamStephen A ByzekLi Ping TangJohn E TrombleyLawrence RasmussenTrenton SchoebHui Min LeungGuillermo J TearneyS Vamsee RajuSteven M RowePublished in: The European respiratory journal (2022)
The pharmacologic reversal of acquired CFTR dysfunction is beneficial against pathological features of chronic bronchitis in a COPD ferret model.