Clinical determinants and prognostic implications of renin and aldosterone in patients with symptomatic heart failure.

Masatake KobayashiSusan StienenJozine M Ter MaatenKenneth DicksteinNilesh J SamaniChim C LangLeong L NgStefan D AnkerMacro MetraGregoire Preud'hommeKevin DuarteZohra LamiralNicolas GirerdPatrick RossignolDirk J van VeldhuisenAdriaan A VoorsFaiez ZannadJoão Pedro Ferreira

Published in: ESC heart failure (2020)

Circulating levels of renin and aldosterone were associated with both the disease severity and use of MRAs. By reflecting both the disease and its treatments, the prognostic discrimination of these biomarkers was poor. Our data suggest that the "point" measurement of renin and aldosterone in HF is of limited clinical utility.

Keyphrases

angiotensin ii
angiotensin converting enzyme
heart failure
acute heart failure
electronic health record
big data
left ventricular
machine learning
artificial intelligence
data analysis
cardiac resynchronization therapy