Microstructural changes precede depression in patients with relapsing-remitting Multiple Sclerosis.

Frank RiemerEllen SkorveOfer Pasternak Fulvio Zaccagna Astri Johansen LundervoldØivind TorkildsenKjell-Morten MyhrRenate Grüner

Published in: Communications medicine (2023)

Our data suggests a relationship between higher levels of free-water in the subcortical structures in an early stage of Multiple Sclerosis and depression symptoms at a later stage of the disease.

Keyphrases

multiple sclerosis
white matter
early stage
sleep quality
depressive symptoms
big data
squamous cell carcinoma
sentinel lymph node
mass spectrometry
rectal cancer