Prognostic Value of MMP-9 -1562 C/T Gene Polymorphism in Patients With Sepsis.

César Bermúdez-MejíaMelissa F Torres-CordónSilvia Becerra-BayonaCarolina María PáezClara Inés VargasMaría Eugenia CárdenasSergio Eduardo SerranoIngrid BaqueroRuth Martínez-VegaRichard SchulzRamses IlarrazaAntonio Pazin FilhoDiego Torres-Dueñas

Published in: Biomarker insights (2019)

We concluded that there was no association between the SNP MMP9 -1562 C/T and sepsis or between the SNP MMP9 -1562 C/T and sepsis mortality in the Northeastern Colombian septic patient cohort. Further research is needed to clarify the correlation among sepsis, genetic factors with allele T and MMP-9 plasma concentration.

Keyphrases

acute kidney injury
septic shock
intensive care unit
genome wide
cell migration
cardiovascular events
dna methylation
gene expression
cardiovascular disease
risk factors