In vivo multiphoton imaging for non-invasive time course assessment of retinoids effects on human skin.
Emmanuelle Tancrède-BohinThérèse BaldeweckSébastien BrizionEtienne DecencièreSteeve VictorinBlandine NgoEdouard RaynaudLuc SouverainMartine BagotAna-Maria PenaPublished in: Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) (2020)
With a novel 3D descriptor of melanin z-epidermal distribution, in vivo multiphoton imaging allows demonstrating that daily usage of retinoids counteracts aging by acting not only on epidermal morphology, but also on melanin that is shown to accumulate in the supra-basal layers with time.
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