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Prevention of allergy by virus-like nanoparticles (VNP) delivering shielded versions of major allergens in a humanized murine allergy model.

Bernhard KratzerCordula KöhlerSandra HoferUrsula SmoleDoris TrapinJagoba IturriDietmar PumPhilip KienzlAdelheid Elbe-BuergerPia GattingerIrene MittermannBirgit LinhartGabriele GadermaierBeatrice Jahn-SchmidAlina NeunkirchnerRudolph ValentaWinfried F Pickl
Published in: Allergy (2018)
Virus-like nanoparticles represent a novel and versatile platform for the in vivo delivery of allergens to selectively target T cells and prevent allergies without inducing allergic reactions or allergic sensitization.
Keyphrases
  • atopic dermatitis
  • allergic rhinitis
  • infectious diseases
  • high throughput
  • walled carbon nanotubes
  • disease virus
  • monoclonal antibody