Prevention of allergy by virus-like nanoparticles (VNP) delivering shielded versions of major allergens in a humanized murine allergy model.
Bernhard KratzerCordula KöhlerSandra HoferUrsula SmoleDoris TrapinJagoba IturriDietmar PumPhilip KienzlAdelheid Elbe-BuergerPia GattingerIrene MittermannBirgit LinhartGabriele GadermaierBeatrice Jahn-SchmidAlina NeunkirchnerRudolph ValentaWinfried F PicklPublished in: Allergy (2018)
Virus-like nanoparticles represent a novel and versatile platform for the in vivo delivery of allergens to selectively target T cells and prevent allergies without inducing allergic reactions or allergic sensitization.