dGTP-Templated Luminescent Gold Nanocluster-Based Composite Nanoparticles for Cancer Theranostics.

Bandhan ChatterjeeArchita GhoshalArun Chattopadhyay Siddhartha Sankar Ghosh

Published in: ACS biomaterials science & engineering (2018)

dGTP-templated facile synthesis of luminescent gold nanoclusters (Au NCs) in the presence of cisplatin following PEG coating developed spherical composite NPs. The composite NPs delivered cisplatin efficiently into HeLa cells to induce apoptosis-mediated cell death, and simultaneously bioimaged the cellular uptake.

Keyphrases

cell cycle arrest
cell death
sensitive detection
pi k akt
quantum dots
energy transfer
induced apoptosis
papillary thyroid
oxidative stress
metal organic framework
silver nanoparticles
drug delivery
squamous cell carcinoma
young adults
visible light