Sinapic Acid Inhibits IL-1β-Induced Apoptosis and Catabolism in Nucleus Pulposus Cells and Ameliorates Intervertebral Disk Degeneration.

Jin-Feng HuangXuan-Qi ZhengJia-Liang LinKai Zhang Hai-Jun TianWen-Xian ZhouHui WangZe GaoHai-Ming JinAi-Min Wu

Published in: Journal of inflammation research (2020)

In conclusion, we demonstrated that SA could protect the degeneration of NP cells and revealed the underlying mechanism of SA on Nrf2 activation in NP cells.

Keyphrases

induced apoptosis
endoplasmic reticulum stress
oxidative stress
signaling pathway
cell cycle arrest
cell death
cell proliferation