Epidemiology and precision of SARS-CoV-2 detection following lockdown and relaxation measures.

Karoline LeuzingerRainer GosertKirstine K SøgaardKlaudia NaegeleJulia BielickiTim RoloffRoland BingisserChristian H NickelNina KhannaSarah Tschudin SutterAndreas F WidmerKatharina RentschHans ParggerMartin SiegemundDaiana StolzMichael TammStefano BassettiMichael OsthoffManuel BattegayAdrian EgliHans H Hirsch

Published in: Journal of medical virology (2020)

Manual and automated assays significantly correlated qualitatively and quantitatively. Following a successful lockdown, declining positive predictive values require independent dual-target confirmation for reliable assessment. Confirmatory and quantitative follow-up testing should be obtained within <5 days and consider lower respiratory fluids in symptomatic patients with SARS-CoV-2-negative NOPS.

Keyphrases

sars cov
high throughput
respiratory syndrome coronavirus
machine learning
deep learning
risk factors
high resolution
loop mediated isothermal amplification
real time pcr
mass spectrometry
coronavirus disease
quantum dots