Blimp-1 is a prognostic indicator for progression of cervical intraepithelial neoplasia grade 2.

Mayumi SaitoAarthi RajeshCarrie InnesRachael van der GriendPeter FitzgeraldBryony SimcockPeter SykesMerilyn Hibma

Published in: Journal of cancer research and clinical oncology (2022)

CIN2 progression is associated with high numbers of Blimp-1 positive cells in the lesion. Detection of Blimp-1 in the lesion may have utility as a prognostic test to inform the need to treat CIN2.

Keyphrases

high grade
induced apoptosis
cell cycle arrest
loop mediated isothermal amplification
oxidative stress
signaling pathway
label free
cell death
cell proliferation
real time pcr