Atypical Presentation of Acute Suppurative Otitis Media with Facial Palsy: Extra Medullary Manifestation of AML in Temporal Bone.
Ripu Daman AroraS B NidhinNitin M NagarkarAmit Kumar BanjarePublished in: Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India (2024)
Acute Myeloid Leukemia (AML) is the most common leukemia observed in the adult population, accounting for 80% of all leukemia cases. Extramedullary involvement in AML, where leukemic cells are found in organs or tissues outside the blood or bone marrow, is a rare occurrence [1]. The most frequent sites of extramedullary disease include the skin, central nervous system (CNS), and lymph nodes [2, 3]. In this case report, we present an instance of extramedullary AML in the temporal bone, which initially presented with symptoms such as earache, discharge, and facial asymmetry, mimicking acute suppurative otitis media with facial palsy. The patient underwent mastoid exploration and facial nerve decompression. A post-operative bone marrow biopsy confirmed the diagnosis of AML, leading to the initiation of chemotherapy. The patient is currently under follow-up care.
Keyphrases
- acute myeloid leukemia
- soft tissue
- case report
- bone marrow
- allogeneic hematopoietic stem cell transplantation
- liver failure
- lymph node
- mesenchymal stem cells
- bone mineral density
- respiratory failure
- healthcare
- induced apoptosis
- palliative care
- drug induced
- gene expression
- risk assessment
- blood brain barrier
- minimally invasive
- hepatitis b virus
- intensive care unit
- depressive symptoms
- quality improvement
- cell cycle arrest
- body composition
- cell death
- health insurance
- bone regeneration
- postmenopausal women
- cell proliferation
- peripheral nerve
- sleep quality
- sentinel lymph node
- affordable care act