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Identification of Novel Associations and Localization of Signals in Idiopathic Inflammatory Myopathies Using Genome-Wide Imputation.

Simon RothwellChristopher I AmosFrederick W MillerLisa G RiderIngrid E LundbergPeter K GregersenJiri VencovskyNeil McHughVidya LimayeAlbert Selva O'CallaghanMichael G HannaPedro M MachadoLauren M PachmanAnn M ReedØyvind MolbergOlivier BenvenistePernille MathiesenTimothy RadstakeAndrea DoriaJan L De BleeckerBoel De PaepeBritta MaurerWilliam E OllierLeonid PadyukovTerrance P O'HanlonAnnette LeeLucy R WedderburnHector ChinoyJanine A Lambnull null
Published in: Arthritis & rheumatology (Hoboken, N.J.) (2022)
We found novel and strong associations in IIM and PM and localized signals to single genes and immune cell types.
Keyphrases
  • genome wide
  • dna methylation
  • bioinformatics analysis
  • copy number
  • gene expression
  • risk assessment
  • polycyclic aromatic hydrocarbons