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Pneumatosis intestinalis induced by osimertinib in a patient with lung adenocarcinoma harbouring epidermal growth factor receptor gene mutation with simultaneously detected exon 19 deletion and T790 M point mutation: a case report.

Yuki NukiiAtsushi MiyamotoSayaka MochizukiShuhei MoriguchiYui TakahashiKazumasa OgawaKyoko MuraseShigeo HanadaHironori UrugaHisashi TakayaNasa MorokawaKazuma Kishi
Published in: BMC cancer (2019)
Pneumatosis intestinalis should be noted as an important adverse event that can occur with administration of osimertinib; thus far, such an event has never been reported. This was a valuable case in which osimertinib was successfully restarted after complete recovery from pneumatosis intestinalis, such that further extended administration of osimertinib was achieved.
Keyphrases
  • epidermal growth factor receptor
  • advanced non small cell lung cancer
  • tyrosine kinase
  • small cell lung cancer
  • case report
  • emergency department
  • drug induced