Pneumatosis intestinalis induced by osimertinib in a patient with lung adenocarcinoma harbouring epidermal growth factor receptor gene mutation with simultaneously detected exon 19 deletion and T790 M point mutation: a case report.
Yuki NukiiAtsushi MiyamotoSayaka MochizukiShuhei MoriguchiYui TakahashiKazumasa OgawaKyoko MuraseShigeo HanadaHironori UrugaHisashi TakayaNasa MorokawaKazuma KishiPublished in: BMC cancer (2019)
Pneumatosis intestinalis should be noted as an important adverse event that can occur with administration of osimertinib; thus far, such an event has never been reported. This was a valuable case in which osimertinib was successfully restarted after complete recovery from pneumatosis intestinalis, such that further extended administration of osimertinib was achieved.