Metyrosine-associated endocrinological changes in pheochromocytoma and paraganglioma.
Yuko MatsuoKenji AshidaAyako NagayamaKanoko MoritakaMizuki GobaruJunichi YasudaNaoyuki OgasawaraHirofumi KuroseKatsuaki ChikuiShimpei IwataYukihiro InoguchiNao HasuzawaSeiichi MotomuraTsukasa IgawaMasatoshi NomuraPublished in: Endocrine oncology (Bristol, England) (2023)
Metyrosine significantly reduced catecholamines in patients with pheochromocytoma/paraganglioma and ensured the safety of the surgery. Adjustment of metyrosine administration may make surgical pretreatment more effective in achieving stabilized blood pressure and improving glucose metabolism. Endocrine parameters may manifest as the systemic effects of metyrosine administration.