Effect of renal ischaemia/reperfusion-induced acute kidney injury on pharmacokinetics of midazolam in rats.
Ayako TokunagaHirotaka MiyamotoShintaro FumotoKoyo NishidaPublished in: The Journal of pharmacy and pharmacology (2019)
These results indicated that the displacement of albumin-bound MDZ by IS changed the unbound fraction of MDZ and elevated the T/P ratio of MDZ in I/R rats.