Effect of renal ischaemia/reperfusion-induced acute kidney injury on pharmacokinetics of midazolam in rats.

Ayako TokunagaHirotaka Miyamoto Shintaro Fumoto Koyo Nishida

Published in: The Journal of pharmacy and pharmacology (2019)

These results indicated that the displacement of albumin-bound MDZ by IS changed the unbound fraction of MDZ and elevated the T/P ratio of MDZ in I/R rats.

Keyphrases

acute kidney injury
cardiac surgery
acute myocardial infarction
high glucose
cerebral ischemia
heart failure
acute ischemic stroke
brain injury
percutaneous coronary intervention