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Thermal Liquid Biopsy (TLB) of Blood Plasma as a Potential Tool to Help in the Early Diagnosis of Multiple Sclerosis.

Ferdinanda AnnesiSonia Hermoso-DuránBruno RizzutiRosalinda BrunoDomenico PirritanoAlfredo PetroneFrancesco Del GiudiceJorge OjedaSonia VegaOscar Sanchez-GraciaAdrián Velázquez-CampoyOlga AbiánRita Guzzi
Published in: Journal of personalized medicine (2021)
Our results suggest that TLB can be applied to MS, especially in an initial phase of the disease when diagnosis is difficult and yet more important (in such cases, accuracy of prediction is close to 80%), as well as in personalized patient periodic monitoring. The next step will be determining its utility in differentiating between MS and other disorders, in particular in inflammatory diseases.
Keyphrases
  • multiple sclerosis
  • mass spectrometry
  • white matter
  • ms ms
  • case report
  • oxidative stress
  • ultrasound guided
  • ionic liquid
  • fine needle aspiration
  • magnetic resonance imaging
  • risk assessment
  • computed tomography