UBE2T promotes stage I lung adenocarcinoma progression through PBX1 ubiquitination and PBX1/RORA regulation.
Yujie DengXiaohui ChenXuzheng ChenChuanzhong HuangZhiguang ZhangZhenguo XuXiurong WangJiamin WuLi LiJun SongRuixiang ZhouPublished in: BMC cancer (2024)
The oncogenic role of UBE2T and the UBE2T-PBX1-RORA axis in driving malignant progression in Stage I LUAD had been established. UBE2T might be a novel and promising therapeutic target for LUAD treatment.
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