Plectin plays a role in the migration and volume regulation of astrocytes: a potential biomarker of glioblastoma.
Maja ŽugecBorut FurlaniMaria J CastañonBoštjan RituperIrmgard FischerGiuseppe BroggiRosario CaltabianoGiuseppe M V BarbagalloMichelino Di RosaDaniele TibulloRosalba ParentiNunzio VicarioSaša SimčičVictorio Martin Pozo DevotoGorazd B StokinGerhard WicheJernej JorgačevskiRobert ZorecMaja PotokarPublished in: Journal of biomedical science (2024)
Plectin affects cellular properties that contribute to the pathology of GBM. The observed increase in both cell surface and released plectin levels represents a potential biomarker and therapeutic target in the diagnostics and treatment of GBMs.