LINE retrotransposons characterize mammalian tissue-specific and evolutionarily dynamic regulatory regions.

Maša RollerEricca StamperDiego VillarOsagie IzuoguFergal MartinAisling M RedmondRaghavendra RamachanderanLouise HarewoodDuncan T OdomPaul Flicek

Published in: Genome biology (2021)

Our analyses of the tissue-specificity and evolutionary stability among promoters and enhancers reveal how specific LINE families have helped shape the dynamic mammalian regulome.

Keyphrases

genome wide
transcription factor
single cell
structural basis