Direct oral anticoagulation in atrial fibrillation and heart valve surgery-a meta-analysis and systematic review.
Stephen GerferIlija DjordjevicKaveh EghbalzadehNavid MaderThorsten WahlersElmar KuhnPublished in: Therapeutic advances in cardiovascular disease (2022)
Cumulative data analysis reveals that DOAC may provide an effective and safe alternative to VKA in patients with AF after surgically implanted bioprosthetic heart valves or repair with AF. Within a relatively heterogeneous study population, this meta-analysis shows a risk reduction of major bleedings and thromboembolic stroke or systemic embolisms for DOAC.
Keyphrases
- atrial fibrillation
- systematic review
- direct oral anticoagulants
- data analysis
- aortic valve
- meta analyses
- oral anticoagulants
- catheter ablation
- mitral valve
- left atrial
- left atrial appendage
- heart failure
- aortic valve replacement
- minimally invasive
- transcatheter aortic valve replacement
- aortic stenosis
- percutaneous coronary intervention
- transcatheter aortic valve implantation
- coronary artery bypass
- acute coronary syndrome
- blood brain barrier
- brain injury