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Direct oral anticoagulation in atrial fibrillation and heart valve surgery-a meta-analysis and systematic review.

Stephen GerferIlija DjordjevicKaveh EghbalzadehNavid MaderThorsten WahlersElmar Kuhn
Published in: Therapeutic advances in cardiovascular disease (2022)
Cumulative data analysis reveals that DOAC may provide an effective and safe alternative to VKA in patients with AF after surgically implanted bioprosthetic heart valves or repair with AF. Within a relatively heterogeneous study population, this meta-analysis shows a risk reduction of major bleedings and thromboembolic stroke or systemic embolisms for DOAC.
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