New findings on presentation and outcome of patients with adrenocortical cancer: results from a national cohort study.
Puglisi SorayaAnna CalabreseFrancesco FerraùMaria Antonia VioliMarta LaganàSalvatore GrisantiFilippo CeccatoCarla ScaroniGuido Di DalmaziAntonio StiglianoBarbara AltieriLetizia CanuPaola LoliRosario PivonelloEmanuela ArvatValentina MorelliPaola PerottiVittoria BasilePaola BerchiallaSara UrruCristian FioriFrancesco PorpigliaAlfredo BerrutiAnna PiaGiuseppe ReimondoSalvatore CannavòMassimo TerzoloPublished in: The Journal of clinical endocrinology and metabolism (2023)
Our study shows that ACC is a sex-related disease and demonstrates that an incidental presentation is associated with a better outcome. Given the correlation between RFS and OS, RFS may be used as a surrogate end-point in clinical studies.