Reduced Cortico-Cortical Resting-State Connectivity in Sensory Systems is related to Bodily Pain in Juvenile Fibromyalgia.

Maria SuñolJon DudleyMichael F PayneHan TongTracy V TingSusmita Kashikar-ZuckRobert C CoghillMarina López-Solà

Published in: Arthritis & rheumatology (Hoboken, N.J.) (2023)

Reduced cortico-cortical sensory integration involving PCL/S1 and spanning the sensory systems may underly critical pain sensory features in youth with JFM. Reduced sensory integration is paralleled by augmented crosstalk between sensory and affective/salience-processing regions, potentially indicating a shift towards more affectively colored sensory experiences to the detriment of specific sensory discrimination. This article is protected by copyright. All rights reserved.

Keyphrases

resting state
functional connectivity
chronic pain
physical activity
neuropathic pain
young adults
bipolar disorder
spinal cord injury
white matter