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Characterization and Control of the Run-and-Tumble Dynamics of Escherichia Coli.

Christina KurzthalerYongfeng ZhaoNan ZhouJana Schwarz-LinekClemence DevaillyJochen ArltJian-Dong HuangWilson C K PoonThomas FranoschJulien TailleurVincent A Martinez
Published in: Physical review letters (2024)
We characterize the full spatiotemporal gait of populations of swimming Escherichia coli using renewal processes to analyze the measurements of intermediate scattering functions. This allows us to demonstrate quantitatively how the persistence length of an engineered strain can be controlled by a chemical inducer and to report a controlled transition from perpetual tumbling to smooth swimming. For wild-type E. coli, we measure simultaneously the microscopic motility parameters and the large-scale effective diffusivity, hence quantitatively bridging for the first time small-scale directed swimming and macroscopic diffusion.
Keyphrases
  • escherichia coli
  • wild type
  • biofilm formation
  • klebsiella pneumoniae
  • cerebral palsy
  • staphylococcus aureus
  • cystic fibrosis
  • genetic diversity