Novel mouse model for cholestasis-induced liver fibrosis resolution by cholecystojejunostomy.

Kenji YoshinoKojiro TauraKeiko IwaisakoYuki MasanoYusuke UemotoYusuke KimuraNguyen Hai NamHiroto NishinoYoshinobu IkenoYukihiro OkudaTakahiro NishioGen YamamotoSatoru SeoShinji Uemoto

Published in: Journal of gastroenterology and hepatology (2021)

Our established G-J anastomosis model is associated with fibrosis resolution and reduced PF activation through reopening of bile duct obstruction and will be valuable for studying the recovery process of cholestatic liver fibrosis.

Keyphrases

liver fibrosis
mouse model
drug induced
single molecule
liver injury
high glucose
diabetic rats
oxidative stress
endothelial cells
stress induced