Sulforaphane Inhibits Autophagy and Induces Exosome-Mediated Paracrine Senescence via Regulating mTOR/TFE3.

Kai ZhengJingxin MaYifei WangZhendan HeKejun Deng

Published in: Molecular nutrition & food research (2020)

This study suggests the important roles of autophagy and exosome-mediated paracrine senescence in cancer therapy and highlights SFN as a potent anti-ESCC drug candidate.

Keyphrases

cancer therapy
cell death
endoplasmic reticulum stress
dna damage
endothelial cells
oxidative stress
signaling pathway
drug delivery
emergency department
anti inflammatory
electronic health record