MR imaging by 3D T1-weighted black blood sequences may improve delineation of therapy-naive high-grade gliomas.

Tom FinckJens GemptClaus ZimmerJan S KirschkeNico Sollmann

Published in: European radiology (2020)

• This study investigated contrast-enhanced (CE) T1-weighted black blood (BB) sequences for improved MRI in patients with therapy-naive high-grade gliomas (HGGs). • Compared with conventionally used turbo field echo (TFE) sequences, CE BB sequences depicted tumor boundaries and spread of HGGs into adjacent parenchyma considerably better, which also showed higher CNRs. • Two enhancing tumor masses and one satellite lesion were exclusively identified in CE BB sequences, but remained undetected in conventionally used CE TFE sequences.

Keyphrases

contrast enhanced
high grade
diffusion weighted
magnetic resonance imaging
magnetic resonance
computed tomography
low grade
diffusion weighted imaging
growth factor
energy transfer
genetic diversity
hiv infected
stem cells
dual energy
mass spectrometry
bone marrow
atomic force microscopy