Positron emission tomography/computed tomography (PET/CT) has dramatically altered the landscape of noninvasive glioma evaluation, offering complementary insights to those gained through magnetic resonance imaging (MRI). PET/CT scans enable a multifaceted analysis of glioma biology, supporting clinical applications from grading and differential diagnosis to mapping the full extent of tumors and planning subsequent treatments and evaluations. With a broad array of specialized radiotracers, researchers and clinicians can now probe various biological characteristics of gliomas, such as glucose utilization, cellular proliferation, oxygen deficiency, amino acid trafficking, and reactive astrogliosis. This review aims to provide a recent update on the application of versatile PET/CT radiotracers in glioma research and clinical practice.
Keyphrases
- pet ct
- positron emission tomography
- computed tomography
- magnetic resonance imaging
- high resolution
- contrast enhanced
- clinical practice
- amino acid
- palliative care
- pet imaging
- type diabetes
- quantum dots
- signaling pathway
- subarachnoid hemorrhage
- magnetic resonance
- metabolic syndrome
- high density
- single cell
- living cells
- diffusion weighted imaging
- photodynamic therapy
- mass spectrometry
- adipose tissue
- fluorescence imaging
- brain injury
- blood brain barrier
- replacement therapy
- fluorescent probe