Diabetes insipidus and Guillain-Barré-like syndrome following CAR-T cell therapy: a case report.
Christian KochJuliane FleischerTodor PopovKarl FrontzekBettina SchreinerPatrick RothMarkus G ManzSimone UnseldAntonia M S MüllerNorman F RusskampPublished in: Journal for immunotherapy of cancer (2023)
This case report highlights the risk of rare but severe neurological adverse events, such as acute GBS or cDI, in patients treated with CAR-T cells. It further underlines the importance of appropriate patient surveillance and systematic reporting of rare complications to eventually improve treatment.
Keyphrases
- case report
- cell therapy
- stem cells
- type diabetes
- liver failure
- mesenchymal stem cells
- cardiovascular disease
- public health
- drug induced
- respiratory failure
- risk factors
- early onset
- adverse drug
- aortic dissection
- hepatitis b virus
- combination therapy
- blood brain barrier
- bone marrow
- acute respiratory distress syndrome
- mechanical ventilation