Biological effects of stored platelet-rich plasma eye-drops in corneal wound healing.
Yuichi OkumuraTakenori InomataKeiichi FujimotoKenta FujioJun ZhuAi YanagawaHurramhon ShokirovaYoshitomo SaitaYohei KobayashiMasahi NagaoHirofumi NishioJaemyoung SungAkie Midorikawa-InomataAtsuko EguchiKen NaginoYasutsugu AkasakiKunihiko HirosawaTianxiang HuangMizu KuwaharaAkira MurakamiPublished in: The British journal of ophthalmology (2022)
PRP eye-drops stored at 4°C for 4 weeks promoted corneal epithelial wound healing with higher levels of growth factors than those observed in AS eye-drops, while maintaining sterility, suggesting that this preparation satisfies the unmet medical needs in the treatment of refractory keratoconjunctival epithelial disorders.