Changes in global DNA methylation and hydroxymethylation in oral mucosa according to tobacco smoke exposure.

Gabriela-Emilia Avram Anca MarcuAlexandra MoatarCorina SamoilaAngela PodariuEdward SeclamanCatalin Marian

Published in: The Journal of international medical research (2021)

Our findings suggest that smoking leads to global reductions in both methylation and hydroxymethylation levels in oral epithelial cells in a manner influenced by the intensity and length of exposure to tobacco smoke.

Keyphrases

dna methylation
genome wide
gene expression
high intensity
smoking cessation
copy number