High Levels of Triggering Receptor Expressed in Myeloid Cells-Like Transcript-1 Positive, but Not Glycoprotein 1b+, Microparticles Are Associated With Poor Outcomes in Acute Respiratory Distress Syndrome.
Angelia D GibsonZaida Bayrón-MarreroBenjamin Nieves-LopezGerónimo Maldonado-MartínezA Valance WashingtonPublished in: Critical care explorations (2024)
Although both αIIbβIIIa+ and TLT+ microparticles (αIIbβIIIa, TLT-1) were associated with mortality, TLT-1+ MPs demonstrated stronger correlations with Acute Physiology and Chronic Health Evaluation III scores, unassisted breathing, and multiple system organ failure. These findings warrant further exploration of the mechanistic role of TLT-1+ PMP in ARDS or acute lung injury progression.
Keyphrases
- acute respiratory distress syndrome
- extracorporeal membrane oxygenation
- mechanical ventilation
- respiratory failure
- induced apoptosis
- public health
- healthcare
- liver failure
- cell cycle arrest
- lipopolysaccharide induced
- drug induced
- mental health
- lps induced
- bone marrow
- acute myeloid leukemia
- cardiovascular events
- dendritic cells
- health information
- oxidative stress
- risk factors
- aortic dissection
- cell death
- risk assessment
- type diabetes
- intensive care unit
- binding protein
- human health
- social media
- glycemic control