Metformin alleviates inflammation in oxazolone induced ulcerative colitis in rats: plausible role of sphingosine kinase 1/sphingosine 1 phosphate signaling pathway.
Nageh Ahmed El-MahdyMagda El-Sayed El-SayadAya Hassan El-KademSally El-Sayed Abu-RishaPublished in: Immunopharmacology and immunotoxicology (2021)
It is revealed that metformin alleviated inflammation and underlying mechanism may result from inhibition of SPHK1/S1P signaling pathway.