Overexpression of Lin28a delays Xenopus metamorphosis and down-regulates albumin independently of its translational regulation domain.

Daniel G GundermannJimena MartínezGenevieve De KervorKarina González-PintoJuan LarraínFernando Faunes

Published in: Developmental dynamics : an official publication of the American Association of Anatomists (2019)

These results suggest that Lin28 delays metamorphosis through regulation of let-7 and that the decrease of the TH carrier albumin is one of the early changes after Lin28 overexpression.

Keyphrases

cell proliferation
transcription factor