Neural tube defects prevalence does not increase after modification of the folic acid fortification program in Chile.
Rosa PardoMarcela VilcaLuis VillarroelTahera DavaljiJohn F ObryckiMaitreyi MazumdarClaudia AvilaCecilia MelladoPublished in: Birth defects research (2022)
Decreasing the concentration of folic acid fortification was not associated with a statistically significant change in the prevalence of NTDs. Mandatory folic acid fortification continues to be a safe and highly effective policy to prevent NTDs. Future studies should evaluate the prevalence of NTDs across Chile and adherence to folic acid fortification mandates.